General Information

  • ID:  hor000260
  • Uniprot ID:  NA
  • Protein name:  Bombesin-like peptide
  • Gene name:  NA
  • Organism:  Canine
  • Family:  Bombesin/neuromedin-B/ranatensin family
  • Source:  animal
  • Expression:  intestinal muscle
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GGQGTVLDKMYPRGNHWAVGHLM
  • Length:  23
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Modulates a variety of biological activities in the gastrointestinal tract and the central nervous system.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor000260_AF2.pdbhor000260_ESM.pdb

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Physical Information

Mass: 291751 Formula: C111H170N34O30S2
Absent amino acids: CEFIS Common amino acids: G
pI: 9.3 Basic residues: 4
Polar residues: 8 Hydrophobic residues: 6
Hydrophobicity: -44.35 Boman Index: -2194
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 63.48
Instability Index: 1524.35 Extinction Coefficient cystines: 6990
Absorbance 280nm: 317.73

Literature

  • PubMed ID:  6853532
  • Title:  Amino Acid Sequences of Three Bombesin-Like Peptides From Canine Intestine Extracts